Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914374 | 0.83 | FFAR1 (0.67) | FFAR1AKR1B1FFAR4MAOB | |
| SCHEMBL1482485 | 0.83 | MRGPRX4 (0.47) | FFAR1MAOB | |
| SCHEMBL1481917 | 0.80 | PARP10 (0.45) | FFAR1MAOB | |
| SCHEMBL1482752 | 0.78 | PARP10 (0.48) | FFAR1MAOB | |
| SCHEMBL2113928 | 0.76 | PTPN7 (0.49) | FFAR1AKR1B1 | |
| SCHEMBL427002 | 0.76 | MAOB (0.74) | MAOB | |
| SCHEMBL30444612 | 0.72 | FFAR1 (0.65) | FFAR1AKR1B1FFAR4 | |
| SCHEMBL6985623 | 0.72 | FFAR1 (0.65) | FFAR1AKR1B1FFAR4 | |
| SCHEMBL30740885 | 0.71 | FFAR1 (0.62) | FFAR1AKR1B1FFAR4TSPODRD3 | |
| SCHEMBL447652 | 0.71 | FFAR1 (0.62) | FFAR1AKR1B1FFAR4TSPODRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |