Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914368 | 0.83 | FFAR1 (0.60) | FFAR1FFAR4AKR1B1MAOB | |
| SCHEMBL6985623 | 0.82 | FFAR1 (0.65) | FFAR1FFAR4AKR1B1RXRARXRB | |
| SCHEMBL30444612 | 0.82 | FFAR1 (0.65) | FFAR1FFAR4AKR1B1RXRARXRB | |
| SCHEMBL4435816 | 0.81 | MAOB (0.57) | FFAR1FFAR4MAOB | |
| SCHEMBL427002 | 0.81 | MAOB (0.74) | MAOB | |
| SCHEMBL20465388 | 0.79 | MAOB (0.76) | RXRARXRBMAOB | |
| SCHEMBL188561 | 0.79 | MAOB (0.55) | MAOB | |
| SCHEMBL18639804 | 0.79 | MAOB (0.55) | MAOB | |
| SCHEMBL2113928 | 0.78 | PTPN7 (0.49) | FFAR1AKR1B1 | |
| SCHEMBL20393245 | 0.77 | MAOB (0.45) | FFAR1FFAR4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |