Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28274058 | 0.82 | ALDH1A1 (0.53) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL28856615 | 0.80 | KIF11 (0.44) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL16256478 | 0.79 | ALDH1A1 (0.50) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL27587036 | 0.79 | PTPN5 (0.59) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL30985262 | 0.77 | KIF11 (0.50) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL28378098 | 0.76 | HDAC4 (0.51) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL7649454 | 0.76 | PTPN5 (0.68) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL200188 | 0.76 | BACE1 (0.49) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL30023786 | 0.74 | KIF11 (0.72) | HDAC4HDAC2HDAC8KIF11ALDH1A1 | |
| SCHEMBL5547288 | 0.74 | KIF11 (0.72) | HDAC4HDAC2HDAC8KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225385-B1 | MADE BY CONDENSING PHOSPHORUS TRICHLORIDE WITH 2,2'-DIMETHYL-4,4'-DIHYDROXY-5,5'-DITERTBUTYLDIPHENYL; ADDED TO PLASTICS, PAINTS, COATINGS, AND OILS TO PROTECT AGAINST DAMAGE CAUSED BY OXYGEN, LIGHT, AND HEAT | CLARIANT GMBH (DE) | 2001-05-01 | — | — | US | disclosed |