SCHEMBL7914744

SCHEMBL7914744

CCOS(=O)(=O)OC(C)=O.[MgH2]

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15211037 0.98 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10CA1CA2
SCHEMBL7010601 0.95 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10CA1CA2
SCHEMBL27660311 0.80 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10CA1CA2
Sulfuric Acid Diethyl Ester SCHEMBL25193310 0.77 CA1 (0.43) ALDH1A1LMNAHSD17B10CA1CA2
SCHEMBL29242383 0.76 CA1 (0.39) ALDH1A1CA1CA2
SCHEMBL114520 0.76 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL1252810 0.76 THRB (0.42) ALDH1A1LMNAHSD17B10CA1CA2
SCHEMBL27260870 0.76 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10CA1CA2
SCHEMBL25504746 0.74 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10CA1CA2
Ammonia Solution, Strong SCHEMBL1943125 0.74 THRB (0.41) ALDH1A1LMNAHSD17B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107430341-A Photosensitive polymer combination, the manufacture method of resin film, the manufacture method of organic semiconductor device and fluoropolymer 旭硝子株式会社 2017-12-01 CN disclosed
CN-107311935-A For synthesizing and using the composition of contrast agent, method and system 蓝瑟斯医学影像公司 2017-11-03 CN disclosed
CN-104803891-B Glucagon antagonist 症变治疗公司 2017-10-20 CN disclosed
CN-105504232-B The new method of copolymer is prepared based on two kinds of different carbon radicals co-coupling reactions 浙江大学 2017-07-18 CN disclosed
CN-105461904-B A kind of new method that polymer is prepared based on carbon radicals coupling reaction 浙江大学 2017-06-20 CN disclosed
CN-105452913-A Optical film, and polarizing plate and liquid crystal display device that use this optical film FUJIFILM CORP 2016-03-30 CN disclosed
CN-105384723-A Liquid crystal compound, liquid crystal composition, polymer and application JNC PETROCHEMICAL CORP 2016-03-09 CN disclosed
CN-102171216-B Polymerizable chiral compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optically anisotropic body ZEON CORP 2014-07-23 CN disclosed
CN-102341380-A Bumetanide, furosemide, piretanide, azosemide, and torsemide analogs, compositions and methods of use NEUROTHERAPEUTICS PHARMA INC 2012-02-01 CN disclosed
CN-1642929-B Kappa-opioid receptor agonists containing 2-phenylbenzothiazoline derivatives SANTEN PHARMACEUTICAL CO LTD 2010-05-12 CN disclosed
US-5268387-A Containing ester or carbamate group ALLERGAN, INC. (US) 1993-12-07 US disclosed
WO-1993021915-A1 PHARMACEUTICAL COMPOSITIONS FOR INHIBITING BONE LOSS CONTAINING 3 AND 4-SUBSTITUTED 2(5H)-FURANONES ALLERGAN, INC. (US) 1993-11-11 WO disclosed
EP-0524979-A4 2(5H)-FURANONES SUBSTITUTED IN THE 5 AND OR IN THE 4 POSITION, AS ANTI-INFLAMMATORY AGENTS 1993-03-10 EP disclosed
EP-0524979-A1 2(5H)-FURANONES SUBSTITUTED IN THE 5 AND OR IN THE 4 POSITION, AS ANTI-INFLAMMATORY AGENTS ALLERGAN, INC. (US) 1993-02-03 EP disclosed
WO-1991016055-A1 2(5H)-FURANONES SUBSTITUTED IN THE 5 AND OR IN THE 4 POSITION, AS ANTI-INFLAMMATORY AGENTS ALLERGAN, INC. (US) 1991-10-31 WO disclosed
CN-1051731-A Herbicidal compound, its preparation method and methods for using them TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1991-05-29 CN disclosed
EP-0014057-B1 GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-02 EP disclosed
US-4342765-A Guanidine derivatives and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-08-03 US disclosed
US-4278670-A TREATING BACTERIAL INFECTIONS SMITHKLINE CORPORATION (US) 1981-07-14 US disclosed
EP-0014057-A1 Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-08-06 EP disclosed