Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914766 | 1.00 | MAPT (0.38) | MAPTPOLBNPSR1GPR132 | |
| SCHEMBL7901092 | 0.91 | MAPT (0.42) | MAPTPOLBNPSR1 | |
| SCHEMBL7900697 | 0.85 | HPGDS (0.41) | MAPTPOLB | |
| SCHEMBL7907989 | 0.84 | POLB (0.42) | MAPTPOLB | |
| SCHEMBL7907987 | 0.84 | POLB (0.42) | MAPTPOLB | |
| SCHEMBL7907975 | 0.84 | POLB (0.42) | MAPTPOLB | |
| Water SCHEMBL7910665 | 0.84 | POLB (0.41) | MAPTPOLB | |
| SCHEMBL7901161 | 0.83 | MAPT (0.42) | MAPTPOLBNPSR1 | |
| SCHEMBL7901278 | 0.83 | MAPT (0.42) | MAPTPOLBNPSR1 | |
| SCHEMBL8550835 | 0.81 | MAPT (0.40) | MAPTPOLBNPSR1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |