Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900847 | 0.94 | HPGDS (0.40) | MAPTPOLBHPGDS | |
| SCHEMBL7900844 | 0.94 | HPGDS (0.40) | MAPTPOLBHPGDS | |
| SCHEMBL8550839 | 0.89 | HPGDS (0.39) | MAPTPOLBNPSR1HPGDSNPC1 | |
| SCHEMBL7900697 | 0.88 | HPGDS (0.41) | MAPTPOLBHPGDS | |
| SCHEMBL7901092 | 0.81 | MAPT (0.42) | MAPTPOLBNPSR1 | |
| SCHEMBL8551572 | 0.81 | HPGDS (0.38) | HPGDS | |
| SCHEMBL7914766 | 0.81 | MAPT (0.38) | MAPTPOLBNPSR1GPR132 | |
| SCHEMBL7914768 | 0.81 | MAPT (0.38) | MAPTPOLBNPSR1GPR132 | |
| SCHEMBL7907987 | 0.80 | POLB (0.42) | MAPTPOLB | |
| SCHEMBL7907975 | 0.80 | POLB (0.42) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |