SCHEMBL7914800

SCHEMBL7914800

C[Ti](Cl)(Cl)(=Cc1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941402 0.75 SIGMAR1 (0.32) SIGMAR1
SCHEMBL9420397 0.65 HTR2A (0.33) SIGMAR1
SCHEMBL3687659 0.64 HTR2A (0.35) SIGMAR1
SCHEMBL437961 0.64 SIGMAR1 (0.31) SIGMAR1
Benzene SCHEMBL28389034 0.62 SIGMAR1 (0.42) SIGMAR1
Hydrochloric Acid SCHEMBL7914805 0.61 HTR6 (0.34) SIGMAR1
SCHEMBL7520595 0.61 HTR6 (0.33) SIGMAR1
SCHEMBL7770537 0.60 HTR6 (0.33) SIGMAR1
SCHEMBL8160813 0.60 HTR6 (0.33) SIGMAR1
SCHEMBL186866 0.59 HTR2A (0.41) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207774-B1 COPOLYMERIZATION OF ETHYLENE WITH AN .ALPHA.-OLEFIN HAVING THREE OR MORE CARBONS BY USE OF AN OLEFIN POLYMERIZATION CATALYST CONTAINING A METALLOCENE COMPOUND, AN IONIZING IONIC COMPOUD, AND AN ORGANOALUMINUM COMPOUNDTHE METALLO TOSOH CORPORATION (JP) 2001-03-27 US disclosed
US-5817590-A METALLOCENE, IONIZING IONIC COMPOUND, ORGANOALUMINUM COMPOUND, LEWIS BASE TOSOH CORPORATION (JP) 1998-10-06 US disclosed
EP-0612769-B1 Process for producing ethylene alpha-olefin copolymer TOSOH CORP (JP) 1997-11-12 EP disclosed
EP-0648786-B1 Process for producing alpha-olefin polymer TOSOH CORP (JP) 1997-07-16 EP disclosed
US-5576259-A POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE TOSOH CORPORATION (JP) 1996-11-19 US disclosed
EP-0653445-A1 Ethylene/alpha-olefin copolymer Tosoh Corporation (JP) 1995-05-17 EP disclosed
EP-0648786-A1 Process for producing alpha-olefin polymer Tosoh Corporation (JP) 1995-04-19 EP disclosed
EP-0612769-A1 Process for producing ethylene alpha-olefin copolymer TOSOH CORPORATION (JP) 1994-08-31 EP disclosed