Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166721 | 0.81 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7638965 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7159183 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7645141 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7163887 | 0.78 | KMT2A (0.64) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7166469 | 0.78 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6815219 | 0.78 | ALDH1A1 (0.50) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL7914993 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7911948 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7662520 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |