Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166721 | 0.85 | MAPT (0.51) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7638965 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7645141 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7159183 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7166469 | 0.81 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7163887 | 0.81 | KMT2A (0.64) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7911948 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7161939 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7915002 | 0.78 | CYP3A4 (0.41) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7914845 | 0.77 | GRIN1 (0.39) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |