Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912095 | 0.90 | MAPT (0.62) | MAPTLMNATP53KDRMEN1 | |
| SCHEMBL7914832 | 0.89 | MAPT (0.61) | MAPTLMNATP53KDRMEN1 | |
| SCHEMBL7912315 | 0.88 | NPSR1 (0.56) | MAPTLMNATP53KDRENPP3 | |
| SCHEMBL7904976 | 0.87 | MAPT (0.58) | MAPTLMNATP53KDRMEN1 | |
| SCHEMBL7912137 | 0.87 | NPSR1 (0.56) | MAPTTP53KDRKMT2AENPP3 | |
| SCHEMBL7918628 | 0.87 | MAPT (0.81) | MAPTLMNATP53KDRMEN1 | |
| SCHEMBL7904917 | 0.84 | ENPP3 (0.57) | MAPTLMNATP53KDRENPP3 | |
| SCHEMBL7913364 | 0.84 | KDR (0.58) | MAPTLMNATP53KDRPOLB | |
| SCHEMBL7904904 | 0.84 | CA1 (0.50) | MAPTLMNATP53KDRMEN1 | |
| SCHEMBL7915059 | 0.82 | NPSR1 (0.52) | MAPTLMNATP53KDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |