Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914879 | 0.92 | EGFR (0.53) | NPSR1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL7912095 | 0.90 | MAPT (0.62) | NPSR1LMNAALDH1A1HPGDENPP3 | |
| SCHEMBL7914903 | 0.89 | ABCG2 (0.53) | NPSR1LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7914922 | 0.87 | MAPT (0.58) | NPSR1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL7912137 | 0.87 | NPSR1 (0.56) | NPSR1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL7913307 | 0.84 | NPSR1 (0.53) | NPSR1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL7918597 | 0.82 | RXFP1 (0.57) | NPSR1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL7905029 | 0.82 | NPSR1 (0.73) | NPSR1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL7914883 | 0.82 | MAPT (0.62) | NPSR1LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7912149 | 0.81 | THRB (0.50) | NPSR1LMNAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |