Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918665 | 0.92 | HTT (0.60) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL7914925 | 0.84 | NPSR1 (0.78) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL7915135 | 0.83 | NPSR1 (0.65) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL3021712 | 0.80 | HTT (0.73) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL27965124 | 0.79 | KMT2A (0.79) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL7904930 | 0.79 | NPSR1 (1.00) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL7913387 | 0.78 | NPSR1 (0.87) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL27956430 | 0.77 | ALDH1A1 (0.69) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL7915167 | 0.76 | HTT (0.73) | HTTNPSR1LMNAALDH1A1MAPT | |
| SCHEMBL7913323 | 0.76 | KMT2A (0.73) | HTTNPSR1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |