Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913404 | 0.91 | MAPT (0.50) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL7914896 | 0.88 | MAPT (0.58) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL7918649 | 0.86 | MAPT (0.54) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL7915119 | 0.83 | MAPT (0.43) | MAPTGAAHPGDKMT2ALMNA | |
| SCHEMBL7912202 | 0.83 | FLT1 (0.49) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL7913398 | 0.81 | KDR (0.56) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL7914954 | 0.81 | MAPT (0.57) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL7905044 | 0.81 | MAPT (0.55) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL7904976 | 0.81 | MAPT (0.58) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL7913378 | 0.81 | MAPT (0.55) | MAPTGAAHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |