SCHEMBL7915022

SCHEMBL7915022

Nc1cc2ncccc2c2cccnc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.55
MAPT P10636 4/20 0.52
KDM4E B2RXH2 2/20 0.52
HSP90AA1 P07900 5/20 0.50
HSP90AB1 P08238 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
CASP6 P55212 2/20 0.50
HTT P42858 2/20 0.50
APAF1 O14727 1/20 0.50
TDP2 O95551 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
NSD2 O96028 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1097183 0.84 HSP90AA1 (0.59) NR4A2MAPTKDM4EHSP90AA1HSP90AB1
SCHEMBL3382683 0.82 HSP90AA1 (0.58) NR4A2MAPTKDM4EHSP90AA1HSP90AB1
SCHEMBL2884972 0.82 HSP90AA1 (0.58) NR4A2MAPTKDM4EHSP90AA1HSP90AB1
SCHEMBL17066276 0.76 NCF1 (0.48) NR4A2MAPTKDM4EHSP90AA1HSP90AB1
SCHEMBL17173759 0.76 KDM4E (0.52) NR4A2MAPTKDM4EHSP90AA1MEN1
SCHEMBL1389187 0.76 KDM4E (0.52) MAPTKDM4EHSP90AA1HSP90AB1MEN1
SCHEMBL9308262 0.74 HSP90AA1 (0.73) MAPTKDM4EHSP90AA1HSP90AB1MEN1
Dipyridyl SCHEMBL3937916 0.74 HSP90AA1 (0.49) NR4A2MAPTKDM4EHSP90AA1HSP90AB1
Dipyridyl SCHEMBL28127543 0.74 HSP90AA1 (0.49) NR4A2MAPTKDM4EHSP90AA1HSP90AB1
SCHEMBL29661959 0.74 HSP90AA1 (0.70) NR4A2MAPTKDM4EHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed