Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.73 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.73 |
| ▸ | MMP14 | P50281 | 3/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5,6-Dihydroxy-8-Aminoquinoline SCHEMBL5640903 | 0.87 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL12192928 | 0.80 | NSD2 (0.68) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL8626641 | 0.79 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL687239 | 0.77 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL4467681 | 0.77 | KDM4E (0.72) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL30153812 | 0.77 | KDM4E (0.72) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL4457883 | 0.77 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL12292143 | 0.77 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL2110200 | 0.77 | MMP14 (1.00) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 | |
| SCHEMBL18455869 | 0.76 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1MMP14IDO1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350424-A | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0593038-A1 | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-04-20 | — | — | EP | disclosed |