SCHEMBL7915025

SCHEMBL7915025

Oc1c(-c2ccccc2)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
KDM4E B2RXH2 3/20 0.56
MAPT P10636 2/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
MPI P34949 1/20 0.56
NQO1 P15559 1/20 0.54
RECQL P46063 1/20 0.51
GPR84 Q9NQS5 3/20 0.50
CYP11B1 P15538 1/20 0.47
TRPM4 Q8TD43 1/20 0.45
ALOX5 P09917 2/20 0.45
BACE1 P56817 1/20 0.45
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485747 0.94 MEN1 (0.58) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL6130223 0.94 MEN1 (0.58) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL2533194 0.85 MEN1 (0.56) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL25424740 0.84 MEN1 (0.60) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL11906312 0.83 MEN1 (0.55) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL3262604 0.82 MEN1 (0.58) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL29510114 0.82 MEN1 (0.58) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL460619 0.82 TRPM4 (0.52) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL30275493 0.82 MEN1 (0.58) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL31756884 0.82 GPR84 (0.54) MEN1KMT2AKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4188274-A DECARBOXYLATION STANDARD OIL COMPANY (INDIANA) (US) 1980-02-12 US disclosed
US-4174447-A SILVER SALTS OF CARBOXY ACIDS STANDARD OIL COMPANY (INDIANA) (US) 1979-11-13 US disclosed