SCHEMBL460619

SCHEMBL460619

Oc1cc2ccccc2c(O)c1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.52
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
MPI P34949 1/20 0.48
KMT2A Q03164 1/20 0.48
ESR1 P03372 6/20 0.47
ESR2 Q92731 6/20 0.47
NQO1 P15559 1/20 0.47
ALOX5 P09917 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.47
PDE4B Q07343 3/20 0.46
PDE4A P27815 2/20 0.46
PDE4C Q08493 2/20 0.46
PDE4D Q08499 2/20 0.46
NQO2 P16083 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29120666 0.86 ESR1 (0.54) TRPM4MAPTKDM4EMEN1ALDH1A1
SCHEMBL30689894 0.86 ESR1 (0.54) TRPM4MAPTKDM4EMEN1ALDH1A1
SCHEMBL9463316 0.84 TRPM4 (0.52) TRPM4MAPTKDM4EMEN1ALDH1A1
SCHEMBL374808 0.83 ALOX5 (0.52) TRPM4ESR1ESR2NQO1ALOX5
SCHEMBL5478446 0.83 CNR2 (0.50) TRPM4MEN1KMT2ANQO1ALOX5
SCHEMBL7915025 0.82 MEN1 (0.56) TRPM4MAPTKDM4EMEN1ALDH1A1
SCHEMBL5461208 0.81 CYP11B1 (0.59) KDM4ECYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3170245 0.81 KMT2A (0.46) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL22688521 0.81 POLB (0.50) TRPM4MAPTKDM4EMEN1ALDH1A1
SCHEMBL17726753 0.81 CRHBP (0.47) TRPM4MAPTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3414276-A1 INHERENTLY HEALING POLYCARBONATE RESINS SABIC Global Technologies B.V. (NL) 2018-12-19 EP disclosed
WO-2017137951-A1 INHERENTLY HEALING POLYCARBONATE RESINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-17 WO disclosed
US-9045587-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
US-20140363768-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-11 US disclosed
US-8846846-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-30 US disclosed
CN-101173155-B Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH CO LTD 2012-12-19 CN disclosed
US-20120064725-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-15 US disclosed