SCHEMBL7915032

SCHEMBL7915032

Cc1c(C#N)c(O)nc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
KDM4E B2RXH2 5/20 0.56
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
PDE10A Q9Y233 2/20 0.44
KDM4A O75164 1/20 0.43
KDM5B Q9UGL1 1/20 0.43
HTT P42858 2/20 0.41
GPR3 P46089 1/20 0.40
HSD17B10 Q99714 2/20 0.40
ADRA2A P08913 1/20 0.40
ADORA2A P29274 1/20 0.40
ATM Q13315 1/20 0.38
ERN1 O75460 1/20 0.38
HPGD P15428 3/20 0.38
CYP1A2 P05177 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5794239 0.82 KDM4E (0.60) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL3970610 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL7549915 0.80 PDE10A (0.41) ALDH1A1KDM4EMEN1KMT2APDE10A
SCHEMBL6253855 0.79 KDM4E (0.56) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL2639136 0.79 ALDH1A1 (0.56) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL18459144 0.79 KDM4E (0.56) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL4744765 0.79 ALDH1A1 (0.56) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL30315435 0.79 KDM4E (0.56) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL7550340 0.79 PDE10A (0.41) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL7094516 0.78 ALDH1A1 (0.55) ALDH1A1KDM4EMEN1KMT2APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743462-A1 COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS Tay Therapeutics Limited (GB) 2026-05-20 EP disclosed
WO-2025012643-A1 COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS Tay Therapeutics Limited (GB) 2025-01-16 WO disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed