Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549915 | 0.83 | PDE10A (0.41) | PDE10AALDH1A1CYP1A2HTTGPR3 | |
| SCHEMBL7550385 | 0.79 | KDM1A (0.39) | PDE10AALDH1A1CYP1A2HTTKDM4E | |
| SCHEMBL7915032 | 0.79 | ALDH1A1 (0.56) | PDE10AALDH1A1CYP1A2HTTGPR3 | |
| SCHEMBL7548798 | 0.77 | SMN1; SMN2 (0.42) | PDE10AALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL7545823 | 0.77 | PDE10A (0.47) | PDE10AALDH1A1HTTKDM4ETSHR | |
| SCHEMBL13467803 | 0.74 | GPR3 (0.48) | PDE10AELANEALDH1A1CYP1A2HTT | |
| SCHEMBL7548608 | 0.74 | KDM4E (0.45) | PDE10AALDH1A1CYP1A2KDM4ETSHR | |
| SCHEMBL16569894 | 0.72 | TSHR (0.35) | ELANEALDH1A1CYP1A2KDM4ETSHR | |
| SCHEMBL1470735 | 0.71 | ALDH1A1 (0.35) | ELANEALDH1A1CYP1A2GPR3KDM4E | |
| SCHEMBL29690232 | 0.71 | ALDH1A1 (0.35) | ELANEALDH1A1CYP1A2GPR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | claimed |