SCHEMBL7915046

SCHEMBL7915046

CCC(c1cccc(OC#N)c1)[Si](Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.33
PFKFB3 Q16875 1/20 0.32
ALDH1A1 P00352 2/20 0.32
FAAH O00519 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.32
SGMS2 Q8NHU3 1/20 0.31
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915126 0.84 AOC3 (0.34) AOC3PFKFB3ALDH1A1FAAHBCHE
SCHEMBL7916844 0.83 ALDH1A1 (0.33) AOC3ALDH1A1FAAHBCHEACHE
SCHEMBL7914967 0.81 ACHE (0.35) AOC3PFKFB3FAAHBCHEACHE
SCHEMBL7906826 0.81 ALDH1A1 (0.32) ALDH1A1GAA
SCHEMBL7916822 0.75 ACHE (0.42) ALDH1A1ACHEKDM4ETSHRL3MBTL1
SCHEMBL7920309 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EL3MBTL1
SCHEMBL7917060 0.73 KDM4E (0.35) AOC3ALDH1A1FAAHBCHEACHE
SCHEMBL7906843 0.71 ACHE (0.34) AOC3PFKFB3FAAHBCHEACHE
SCHEMBL7914532 0.71 TAAR1 (0.43) ACHE
SCHEMBL1054455 0.70 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed