Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705498 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDPDE10A | |
| SCHEMBL7915231 | 0.75 | TOP2A (0.38) | KDM4EALDH1A1GAAHPGDPOLB | |
| Naphthalene SCHEMBL27472463 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1GAAHPGDPDE10A | |
| SCHEMBL6153175 | 0.71 | APP (0.45) | TLR7TLR8BACE1APP | |
| SCHEMBL7027469 | 0.68 | ELANE (0.39) | KDM4EALDH1A1GAAHPGDBACE1 | |
| SCHEMBL9333487 | 0.67 | LMNA (0.49) | KDM4EALDH1A1HPGDPDE10APOLB | |
| SCHEMBL3402941 | 0.65 | AKR1B1 (0.47) | KDM4EALDH1A1GAAHPGDPOLB | |
| SCHEMBL9424806 | 0.65 | CYP1A2 (0.50) | KDM4EALDH1A1HPGDPDE10AKMT2A | |
| SCHEMBL12088222 | 0.64 | PDE10A (0.47) | KDM4EALDH1A1HPGDPDE10APOLB | |
| SCHEMBL19032295 | 0.63 | EGFR (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218137-B1 | SENSITIVE QUANTITATIVE ANALYSIS USING COMPOUND HAVING A HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND WHICH IS SUBSTITUTED AT DISTAL CARBON WITH PHOSPHATE GROUP AND OXYGEN OR SULFUR GROUP | LUMIGEN, INC. | 2001-04-17 | — | — | US | disclosed |