Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705500 | 0.78 | KDM4E (0.46) | TOP2ATOP2BKMT2AMEN1KDM4E | |
| SCHEMBL7915229 | 0.75 | TLR7 (0.34) | TOP2ATOP2BKMT2AKDM4EGLA | |
| SCHEMBL6153175 | 0.69 | APP (0.45) | — | |
| SCHEMBL1478797 | 0.69 | MEN1 (0.61) | KMT2AMEN1KDM4EGLARXFP1 | |
| SCHEMBL9034439 | 0.64 | ACP1 (0.41) | KMT2AMEN1KDM4EGLAKDM1A | |
| SCHEMBL9333487 | 0.61 | LMNA (0.49) | KMT2AMEN1KDM4EGLALMNA | |
| SCHEMBL4163106 | 0.60 | KDM4E (0.53) | KMT2AMEN1KDM4EGLALMNA | |
| SCHEMBL19032295 | 0.60 | EGFR (0.38) | LMNAMAPTHTT | |
| SCHEMBL28846350 | 0.60 | CYP1A2 (0.54) | KMT2AALDH1A1 | |
| SCHEMBL4149713 | 0.59 | KDM4E (0.51) | KMT2AKDM4EGLALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218137-B1 | SENSITIVE QUANTITATIVE ANALYSIS USING COMPOUND HAVING A HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND WHICH IS SUBSTITUTED AT DISTAL CARBON WITH PHOSPHATE GROUP AND OXYGEN OR SULFUR GROUP | LUMIGEN, INC. | 2001-04-17 | — | — | US | disclosed |