Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP9 | P55211 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7915271 | 0.89 | HRH4 (0.33) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7915447 | 0.89 | HRH4 (0.33) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7370017 | 0.79 | DPP4 (0.38) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7921647 | 0.79 | DPP4 (0.38) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7377206 | 0.78 | F10 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL7375929 | 0.76 | F10 (0.56) | — | |
| Trifluoroacetic Acid SCHEMBL7378459 | 0.76 | F10 (0.51) | — | |
| Trifluoroacetic Acid SCHEMBL7446703 | 0.70 | KDR (0.36) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL7453374 | 0.70 | F10 (0.49) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL7213657 | 0.70 | F10 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | claimed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |