Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7915271 | 1.00 | HRH4 (0.33) | HRH4HRH3METAPAF1MITF | |
| Trifluoroacetic Acid SCHEMBL7915274 | 0.89 | HRH4 (0.36) | HRH4HRH3METAPAF1MITF | |
| Trifluoroacetic Acid SCHEMBL7376993 | 0.80 | GPR6 (0.36) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7370016 | 0.80 | GPR6 (0.36) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7921642 | 0.80 | GPR6 (0.36) | HRH4HRH3APAF1MITFCASP7 | |
| Trifluoroacetic Acid SCHEMBL7377206 | 0.76 | F10 (0.49) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL7375929 | 0.75 | F10 (0.56) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL7378459 | 0.75 | F10 (0.51) | F2F10 | |
| SCHEMBL7378733 | 0.73 | CYP2D6 (0.35) | L3MBTL1F2F10 | |
| SCHEMBL7540081 | 0.73 | CYP2D6 (0.35) | L3MBTL1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | claimed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |