Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7921647

NC1CCN(CCNc2ccncc2)C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.38
DPP7 Q9UHL4 2/20 0.38
DPP8 Q6V1X1 2/20 0.38
DPP9 Q86TI2 2/20 0.38
GPR6 P46095 1/20 0.37
HRH4 Q9H3N8 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
APAF1 O14727 1/20 0.36
MITF O75030 1/20 0.36
CASP7 P55210 1/20 0.36
CASP9 P55211 1/20 0.36
CASP6 P55212 1/20 0.36
CASP8 Q14790 1/20 0.36
F2 P00734 6/20 0.35
PRSS1 P07477 1/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 1/20 0.35
GRIN2B Q13224 1/20 0.35
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7370017 1.00 DPP4 (0.38) DPP4DPP7DPP8DPP9GPR6
SCHEMBL7375396 0.91 MAPT (0.33) DPP4HRH3L3MBTL1CYP2D6CYP2C9
SCHEMBL7413226 0.91 MAPT (0.33) DPP4HRH3L3MBTL1CYP2D6CYP2C9
Trifluoroacetic Acid SCHEMBL7921642 0.87 GPR6 (0.36) DPP4DPP7DPP8DPP9GPR6
Trifluoroacetic Acid SCHEMBL7370016 0.87 GPR6 (0.36) DPP4DPP7DPP8DPP9GPR6
Trifluoroacetic Acid SCHEMBL7376993 0.87 GPR6 (0.36) DPP4DPP7DPP8DPP9GPR6
Trifluoroacetic Acid SCHEMBL7378333 0.79 GPR6 (0.38) GPR6L3MBTL1APAF1MITFCASP7
Trifluoroacetic Acid SCHEMBL7915274 0.79 HRH4 (0.36) HRH4HRH3L3MBTL1APAF1MITF
SCHEMBL7378733 0.79 CYP2D6 (0.35) L3MBTL1F2CYP2D6CYP2C9GRIN2B
SCHEMBL7540081 0.79 CYP2D6 (0.35) L3MBTL1F2CYP2D6CYP2C9GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6281227-B1 INHIBITORS OF THE ACTIVITY OF FACTOR XA. AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-08-28 US disclosed