Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251636 | 0.85 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL4302924 | 0.85 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL22388 | 0.84 | IKBKB (0.67) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL31443745 | 0.84 | IKBKB (0.67) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| Hydrochloric Acid SCHEMBL10504906 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL28115811 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL10683291 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL26291187 | 0.83 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL27828993 | 0.81 | IKBKB (0.50) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL30201832 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3719010-B1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| EP-3719010-B1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-05-17 | — | — | US | disclosed |
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-05-17 | — | — | US | disclosed |
| US-11261170-B2 | Aromatic compound, pharmaceutical composition and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-03-01 | — | — | US | disclosed |
| CN-111148742-B | Aromatic compound and pharmaceutical composition and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| EP-3719010-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |
| EP-3719010-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| US-20100331306-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2010-12-30 | — | — | US | disclosed |
| EP-0872903-B1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | SHINETSU CHEMICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6096144-A | TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | PPARD, PPARA, PPARG | SMN1; SMN2 3861/4885ALDH1A1 679/4885HPGD 801/4885 |
| US-20100331306-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, BCL9, MALT1 | SMN1; SMN2 983/4885ALDH1A1 3890/4885HPGD 2335/4885 |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PPARD, PPARA, PPARG | SMN1; SMN2 3861/4885ALDH1A1 679/4885HPGD 801/4885 |
| US-11261170-B2 | Aromatic compound, pharmaceutical composition and use thereof | PPARD, PPARA, PPARG | SMN1; SMN2 3861/4885ALDH1A1 679/4885HPGD 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.