Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034564 | 0.84 | TSHR (0.68) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL68891 | 0.83 | KDM4E (0.51) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL16234345 | 0.83 | KDM4E (0.51) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL6603045 | 0.82 | KDM4E (0.51) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL5255504 | 0.82 | IKBKB (0.66) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL6097776 | 0.82 | ABCG2 (0.55) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL20098513 | 0.82 | KDM4E (0.57) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL31105839 | 0.82 | KDM4E (0.57) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL4302924 | 0.81 | ALDH1A1 (0.67) | SMN1; SMN2MAPTRAB9AHTTKDM4E | |
| SCHEMBL7915323 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTRAB9AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| EP-4377313-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |