SCHEMBL7915453

SCHEMBL7915453

Cc1nc(N)sc1/N=N/c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 14/20 0.71
MAPT P10636 14/20 0.71
MEN1 O00255 13/20 0.71
TDP1 Q9NUW8 11/20 0.71
RAB9A P51151 9/20 0.71
NPC1 O15118 7/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
ALOX12 P18054 2/20 0.71
NFKB1 P19838 2/20 0.71
GFER P55789 1/20 0.71
NFKB2 Q00653 1/20 0.71
RELA Q04206 1/20 0.71
GAA P10253 2/20 0.53
RXFP1 Q9HBX9 1/20 0.53
MAPK1 P28482 8/20 0.51
ALDH1A1 P00352 5/20 0.51
LMNA P02545 5/20 0.51
HPGD P15428 3/20 0.51
GBA1 P04062 1/20 0.51
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915456 1.00 KMT2A (0.71) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL15604010 0.75 RAB9A (0.60) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL10536233 0.72 MEN1 (0.55) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL10536251 0.71 MAPT (0.60) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL10154437 0.71 MAPT (0.60) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL30365137 0.71 MAPT (0.54) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL22650273 0.70 MAPT (0.51) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL8854085 0.67
Azobenzene SCHEMBL11339482 0.67 ALDH1A1 (0.92) KMT2AMAPTMEN1TDP1RAB9A
Azobenzene SCHEMBL11339490 0.67 ALDH1A1 (0.92) KMT2AMAPTMEN1TDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed