Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919653 | 0.92 | TMEM97 (0.62) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL7916125 | 0.92 | HDAC3 (0.60) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL3570124 | 0.90 | LMNA (0.65) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL17448248 | 0.89 | RAB9A (0.68) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9053101 | 0.89 | LMNA (0.66) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL7037787 | 0.88 | LMNA (0.62) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL7916058 | 0.86 | TMEM97 (0.62) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL3704980 | 0.85 | MAPT (0.68) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL10897096 | 0.85 | TMEM97 (0.54) | TMEM97SIGMAR1MAPTRAB9ANPC1 | |
| SCHEMBL2717007 | 0.84 | TMEM97 (0.68) | TMEM97SIGMAR1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |