SCHEMBL7915702

SCHEMBL7915702

O=c1c(OO)ccc2[nH]c3ccccc3cc1-2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 4/20 0.51
CHEK1 O14757 1/20 0.51
KDM4E B2RXH2 6/20 0.44
MAPT P10636 5/20 0.44
RAB9A P51151 4/20 0.44
HPGD P15428 4/20 0.44
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
DAO P14920 2/20 0.42
BRD4 O60885 2/20 0.42
DDO Q99489 1/20 0.42
NPC1 O15118 3/20 0.41
FLT3 P36888 2/20 0.40
HSD17B10 Q99714 2/20 0.39
LMNA P02545 2/20 0.39
PDGFRB P09619 1/20 0.39
FGFR1 P11362 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8049852 0.85 KDR (0.49) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL355568 0.85 RAB9A (0.59) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL9690611 0.80 KDR (0.56) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL3735366 0.80 KDR (0.56) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL3859295 0.80 KDR (0.56) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL5688592 0.78 KDR (0.42) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL973208 0.78 KDR (0.50) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL3234457 0.76 KDR (0.56) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL71078 0.76 KDR (0.56) KDRCHEK1KDM4EMAPTRAB9A
SCHEMBL354610 0.76 KDR (0.56) KDRCHEK1KDM4EMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed