Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915702 | 0.78 | KDR (0.51) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL355568 | 0.75 | RAB9A (0.59) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL8049852 | 0.73 | KDR (0.49) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL3750862 | 0.72 | KDR (0.40) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL3735366 | 0.70 | KDR (0.56) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL9690611 | 0.70 | KDR (0.56) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL6510708 | 0.69 | KDR (0.50) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL71078 | 0.68 | KDR (0.56) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL3234457 | 0.68 | KDR (0.56) | KDRCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL354610 | 0.68 | KDR (0.56) | KDRCHEK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625134-A2 | SUBSTITUTED PHOSPHONATE FLUORESCENT SENSORS AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101579-A2 | SUBSTITUTED PHOSPHONATE FLUORESCENT SENSORS AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2004-11-25 | — | — | WO | disclosed |