Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917214 | 0.85 | ALDH1A1 (0.51) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL11229124 | 0.83 | DRD4 (0.55) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL27886642 | 0.78 | CA9 (0.61) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL9080916 | 0.78 | DRD4 (0.53) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL7907620 | 0.78 | CA9 (0.69) | KDM4EALDH1A1CA12CA9HPGD | |
| SCHEMBL7917887 | 0.78 | CA12 (0.52) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL11229120 | 0.76 | CA12 (0.53) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL8834873 | 0.75 | CA12 (0.58) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL10024912 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1DRD4CA12CA9 | |
| SCHEMBL9081412 | 0.74 | ALDH1A1 (0.55) | KDM4EALDH1A1DRD4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |