Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 16/20 | 0.58 |
| ▸ | CA9 | Q16790 | 16/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834885 | 0.86 | CA12 (0.56) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL11229120 | 0.84 | CA12 (0.53) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL7917887 | 0.82 | CA12 (0.52) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL9080916 | 0.80 | DRD4 (0.53) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL27886642 | 0.77 | CA9 (0.61) | CA12CA9KDM4EALDH1A1DRD4 | |
| SCHEMBL11229124 | 0.76 | DRD4 (0.55) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL9081412 | 0.76 | ALDH1A1 (0.55) | CA12CA9KDM4EALDH1A1DRD4 | |
| SCHEMBL7915734 | 0.75 | KDM4E (0.48) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL22275005 | 0.75 | CA12 (0.67) | CA12CA9SNCAKDM4EALDH1A1 | |
| SCHEMBL10024912 | 0.74 | KDM4E (0.64) | CA12CA9KDM4EALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |