Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736602 | 0.83 | LMNA (0.44) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL15536776 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL7540032 | 0.81 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL10656588 | 0.81 | LMNA (0.52) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11741360 | 0.78 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL10928582 | 0.78 | LMNA (0.47) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11739898 | 0.77 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL12500772 | 0.77 | LMNA (0.56) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL12324662 | 0.77 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL3625296 | 0.77 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | claimed |
| JP-62178573-A | — | — | None | — | — | JP | disclosed |
| JP-57085374-A | — | — | None | — | — | JP | disclosed |
| JP-52151181-A | — | — | None | — | — | JP | disclosed |
| JP-3038573-A | — | — | None | — | — | JP | disclosed |
| JP-61065890-A | — | — | None | — | — | JP | disclosed |
| JP-58072569-A | — | — | None | — | — | JP | disclosed |
| US-20240398966-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2024-12-05 | — | — | US | disclosed |
| US-11998610-B2 | Conjugates and methods of using the same | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-3836971-A1 | CONJUGATES AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2021-06-23 | — | — | EP | disclosed |
| US-4792607-A | ANTICANCER MEDICINE INTERRMEDIATES | CHISSO CORPORATION (JP) | 1988-12-20 | — | — | US | disclosed |
| US-4778797-A | Organo-silicon compounds, process for the manufacture of same, and anti-tumor agent comprising the compound | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |
| JP-S62178573-A | 5-FLUOROURACIL DERIVATIVE AND MEDICINAL PHARMACEUTICAL CONTAINING SAID DERIVATIVE | TERUMO CORP | 1987-08-05 | — | — | JP | disclosed |
| EP-0178076-A2 | Organo-silicone compounds, process for their manufacture, and pharmaceutical compositions thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1986-04-16 | — | — | EP | disclosed |
| JP-S6165890-A | NOVEL ORGANIC SILICON COMPOUND, ITS PRODUCTION AND ANTITUMOR AGENT CONTAINING SAME AS ACTIVE INGREDIENT | SANWA KAGAKU KENKYUSHO:KK | 1986-04-04 | — | — | JP | disclosed |
| US-4497815-A | 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the carcinostatic agents containing same as active ingredients | Ozaki, Shoichiro (JP) | 1985-02-05 | — | — | US | disclosed |
| JP-S5872569-A | 5-FLUOROURACIL DERIVATIVE, ITS PREPARATION AND CARCINOSTATIC AGENT | OZAKI SHOICHIRO | 1983-04-30 | — | — | JP | disclosed |
| JP-S5785374-A | 5-FLUOROURACIL DERIVATIVE AND ITS PREPARATION | MITSUI TOATSU CHEM INC | 1982-05-28 | — | — | JP | disclosed |
| JP-S52151181-A | 1-CHLOROCARBONYL-5-FLUOROURACIL AND PREPARATION THEREOF | MITSUI TOATSU CHEM INC | 1977-12-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11998610-B2 | Conjugates and methods of using the same | CD47, CD44, CD74 | LMNA 2941/4885SMN1; SMN2 1714/4885CYP3A4 2819/4885 |
| US-20240398966-A1 | CONJUGATES AND METHODS OF USING THE SAME | CD47, CD44, CD74 | LMNA 2941/4885SMN1; SMN2 1714/4885CYP3A4 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.