SCHEMBL10656588

SCHEMBL10656588

CC(=O)n1cc(F)c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ CYP2D6 P10635 1/20 0.52
▸ MAPK3 P27361 1/20 0.52
▸ ASAH1 Q13510 1/20 0.52
▸ SQOR Q9Y6N5 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ GRIA1 P42261 1/20 0.44
▸ GRIA2 P42262 1/20 0.44
▸ GRIA3 P42263 1/20 0.44
▸ GRIA4 P48058 1/20 0.44
▸ GRIK5 Q16478 1/20 0.44
▸ TSHR P16473 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ PMP22 Q01453 1/20 0.42
▸ HBB P68871 1/20 0.42
▸ KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28372215 0.82 LMNA (0.48) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL7764701 0.82 LMNA (0.48) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL11741360 0.81 LMNA (0.61) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL7915827 0.81 LMNA (0.49) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL7540032 0.81 LMNA (0.49) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL11739898 0.80 LMNA (0.49) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL6713750 0.78 MAPK1 (0.42) LMNA
SCHEMBL10459087 0.78 ASAH1 (0.72) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL11024545 0.78 LMNA (0.61) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3
SCHEMBL11092234 0.78 LMNA (0.57) LMNASMN1; SMN2CYP3A4CYP2D6MAPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57024369-A — — None — — JP disclosed
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF SHIVALILA CHIKDU SHAKTI (US) 2025-10-02 — — US disclosed
US-20250262235-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD (SG) 2025-08-21 — — US disclosed
US-20250135036-A1 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2025-05-01 — — US disclosed
EP-4522744-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2025-03-19 — — EP disclosed
EP-4507700-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO Wave Life Sciences Ltd. (SG) 2025-02-19 — — EP disclosed
CN-119452084-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2025-02-14 — — CN disclosed
CN-119317632-A Oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2025-01-14 — — CN disclosed
EP-4404942-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-31 — — EP disclosed
WO-2023220428-A1 COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 — — WO disclosed
WO-2023201095-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-10-19 — — WO disclosed
WO-2023049477-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-03-30 — — WO disclosed
EP-0265506-A1 A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER FARMACEUTISK LABORATORIUM FERRING A/S (DK) 1988-05-04 — — EP disclosed
WO-1987006581-A1 A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER FARMACEUTISK LABORATORIUM FERRING A/S (DK) 1987-11-05 — — WO disclosed
US-4528372-A N-Phthalidyl-5-fluorouracils GRELAN PHARMACEUTICAL CO., LTD. (JP) 1985-07-09 — — US disclosed
EP-0062068-B1 N-PHTHALIDYL-5-FLUOROURACIL DERIVATIVES GRELAN PHARMACEUTICAL CO., LTD. (JP) 1985-06-12 — — EP disclosed
EP-0062068-A1 N-PHTHALIDYL-5-FLUOROURACIL DERIVATIVES GRELAN PHARMACEUTICAL CO., LTD. (JP) 1982-10-13 — — EP disclosed
JP-S5724369-A PYRIMIDINE DERIVATIVE AND ITS PREPARATION TOKYO KINZOKU KOGYO KK 1982-02-08 — — JP disclosed
WO-1979000922-A1 URACIL DERIVATIVES,PROCESS FOR PREPARING THE SAME,AND ONCOTIC PREPARATION THEREOF OKADA T 1979-11-15 — — WO disclosed
US-4088646-A ANTITUMOR AND ANTICARCINOGENIC AGENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF ADAR, NSUN2, RNGTT LMNA 793/4885SMN1; SMN2 218/4885CYP3A4 4641/4885
US-20250262235-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO ADAR, RNGTT, NSUN2 LMNA 1350/4885SMN1; SMN2 292/4885CYP3A4 4584/4885
US-20250135036-A1 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF MECP2, ADAR, NSUN2 LMNA 653/4885SMN1; SMN2 74/4885CYP3A4 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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