Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 1.00 |
| ▸ | ITGAV | P06756 | 20/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553511 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7924358 | 0.88 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL7924352 | 0.88 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL7924362 | 0.88 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL13936149 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7514286 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7514277 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| Trifluoroacetic Acid SCHEMBL7447492 | 0.83 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL6422671 | 0.81 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL6420863 | 0.81 | ITGB3 (1.00) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981546-A | Integrin antagonists | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | claimed |
| US-6211184-B1 | TETRAHYDRO-PYRAZINE OR PYRIMIDINE DERIVATIVES; VITRONECTIN RECEPTOR ANTAGONIST; OSTEOPOROSIS; ANTIINFLAMMATORY, ANTITUMOR AGENTS; ANGIOGENESIS AND RESTENOSIS INHIBITORS | MERCK & CO., INC. | 2001-04-03 | — | — | US | disclosed |
| US-5981546-A | Integrin antagonists | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | disclosed |