Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.79 |
| ▸ | ITGAV | P06756 | 20/20 | 0.79 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.79 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924358 | 1.00 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7924362 | 1.00 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7553511 | 0.88 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7915919 | 0.88 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373199 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7405861 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373207 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7405865 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373202 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL6422671 | 0.79 | ITGB3 (1.00) | ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001524079-A | — | — | 2001-11-27 | — | — | JP | claimed |
| EP-0973396-A4 | A METHOD OF TREATING CANCER | MERCK & CO INC (US) | 2001-02-07 | — | — | EP | claimed |
| EP-0973396-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1998044797-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-10-15 | — | — | WO | claimed |
| EP-0973396-A4 | A METHOD OF TREATING CANCER | MERCK & CO INC (US) | 2001-02-07 | — | — | EP | disclosed |
| EP-0973396-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998044797-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-10-15 | — | — | WO | disclosed |