Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656930 | 0.81 | MGLL (0.37) | TP53TSHRPLA2G4BMAPTCYP3A4 | |
| SCHEMBL6656248 | 0.81 | MGLL (0.37) | TP53TSHRPLA2G4BMAPTCYP3A4 | |
| SCHEMBL6655191 | 0.78 | SLC6A4 (0.39) | SLC6A4THRATHRB | |
| SCHEMBL6676707 | 0.78 | SLC6A4 (0.39) | SLC6A4THRATHRB | |
| SCHEMBL28270199 | 0.76 | NR5A1 (0.47) | TP53TSHRTHRATHRB | |
| SCHEMBL6657628 | 0.76 | NR5A1 (0.35) | CNR2TP53TSHRPLA2G4BMAPT | |
| SCHEMBL6656108 | 0.75 | PTPN11 (0.43) | CNR2FAAHRARB | |
| SCHEMBL8731575 | 0.75 | NR5A1 (0.50) | TP53TSHRTHRATHRBPLA2G4B | |
| SCHEMBL8751857 | 0.75 | NR5A1 (0.50) | TP53TSHRTHRATHRBPLA2G4B | |
| SCHEMBL8751856 | 0.75 | NR5A1 (0.50) | TP53TSHRTHRATHRBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |