Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655191 | 1.00 | SLC6A4 (0.39) | SLC6A4SMN1; SMN2NPSR1CYSLTR2CYSLTR1 | |
| SCHEMBL6656930 | 0.79 | MGLL (0.37) | NPC1LMNARAB9A | |
| SCHEMBL6656248 | 0.79 | MGLL (0.37) | NPC1LMNARAB9A | |
| SCHEMBL7915947 | 0.78 | SLC6A4 (0.39) | SLC6A4THRATHRB | |
| SCHEMBL6659358 | 0.77 | L3MBTL1 (0.36) | — | |
| SCHEMBL6687682 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1CYSLTR2CYSLTR1THRA | |
| SCHEMBL8751850 | 0.75 | THRA (0.51) | SMN1; SMN2NPSR1CYSLTR2CYSLTR1THRA | |
| SCHEMBL8216926 | 0.75 | THRA (0.51) | SMN1; SMN2NPSR1CYSLTR2CYSLTR1THRA | |
| SCHEMBL8751890 | 0.75 | THRA (0.51) | SMN1; SMN2NPSR1CYSLTR2CYSLTR1THRA | |
| SCHEMBL8751869 | 0.75 | THRA (0.51) | SMN1; SMN2NPSR1CYSLTR2CYSLTR1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |