Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905684 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1LMNACYP1A2KDM4E | |
| SCHEMBL8290681 | 0.83 | SMN1; SMN2 (0.76) | SMN1; SMN2RAB9ANPC1HPGDMAPT | |
| SCHEMBL7905681 | 0.83 | HTT (0.71) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL8352827 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1HPGDMAPT | |
| SCHEMBL7913801 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNACYP1A2KDM4E | |
| SCHEMBL7919541 | 0.83 | KDM4E (0.54) | SMN1; SMN2MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL7917566 | 0.82 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNACYP1A2KDM4E | |
| SCHEMBL7919550 | 0.81 | KDM4E (0.52) | SMN1; SMN2ALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL2628188 | 0.80 | POLB (0.59) | SMN1; SMN2RAB9ANPC1HPGDMAPT | |
| SCHEMBL19091783 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |