Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661792 | 0.83 | HTT (0.63) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23336142 | 0.83 | HTT (0.57) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7916079 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30986878 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7919541 | 0.82 | KDM4E (0.54) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3369060 | 0.81 | HTT (0.76) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10684986 | 0.81 | HTT (0.76) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17993501 | 0.81 | HTT (0.65) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4162497 | 0.81 | HTT (0.65) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL169824 | 0.80 | TDP1 (0.76) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |