Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916275 | 0.94 | PLA2G7 (0.51) | RAB9AMAPTNPC1NFKB1NFKB2 | |
| SCHEMBL7916168 | 0.88 | MEN1 (0.50) | RAB9AMAPTNPC1NFKB1NFKB2 | |
| SCHEMBL7916170 | 0.82 | PLA2G7 (0.54) | RAB9AMAPTNPC1NFKB1NFKB2 | |
| SCHEMBL775621 | 0.75 | NPC1 (0.61) | RAB9AMAPTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL18050292 | 0.74 | NPC1 (0.56) | RAB9AMAPTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL18050294 | 0.74 | NPC1 (0.56) | RAB9AMAPTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL7913674 | 0.74 | MAPT (0.50) | RAB9AMAPTNPC1NFKB1NFKB2 | |
| SCHEMBL6551256 | 0.73 | AKR1C1 (0.48) | MAPTKMT2AMEN1POLBPLA2G7 | |
| SCHEMBL10500142 | 0.73 | AKR1C1 (0.48) | MAPTKMT2AMEN1POLBPLA2G7 | |
| SCHEMBL6551351 | 0.72 | AKR1C1 (0.52) | MAPTKMT2AMEN1POLBPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218501-B1 | N-HYDROXYHYDROCARBYL-SUBSTITUTED MALEIMIDE POLYMER OR POLYIMIDE ESTERIFIED WITH CINNAMIC ACID DERIVATIVE | CHEIL INDUSTRIES INC. (KR) | 2001-04-17 | — | — | US | disclosed |