SCHEMBL7916168

SCHEMBL7916168

O=C(O)C(=Cc1ccccc1)OC(=O)c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
PLA2G7 Q13093 1/20 0.47
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
PKM P14618 1/20 0.44
MAPT P10636 2/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
AKR1C1 Q04828 2/20 0.42
PTGS2 P35354 2/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C3 P42330 1/20 0.40
LMNA P02545 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916170 0.94 PLA2G7 (0.54) MEN1KMT2APOLBPLA2G7NPC1
SCHEMBL7916266 0.88 RAB9A (0.47) MEN1KMT2APOLBPLA2G7NPC1
SCHEMBL7916275 0.82 PLA2G7 (0.51) MEN1KMT2APOLBPLA2G7NPC1
SCHEMBL775621 0.77 NPC1 (0.61) MEN1KMT2APOLBPLA2G7NPC1
SCHEMBL12485904 0.75 MEN1 (0.81) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL12485905 0.75 MEN1 (0.81) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL6551351 0.74 AKR1C1 (0.52) MEN1KMT2APOLBPLA2G7ALDH1A1
SCHEMBL2554162 0.74 AKR1C3 (0.52) MEN1KMT2APOLBALDH1A1HTT
SCHEMBL6553166 0.74 AKR1C3 (0.52) MEN1KMT2APOLBALDH1A1HTT
SCHEMBL775620 0.73 CES2 (0.59) MEN1KMT2ANPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218501-B1 N-HYDROXYHYDROCARBYL-SUBSTITUTED MALEIMIDE POLYMER OR POLYIMIDE ESTERIFIED WITH CINNAMIC ACID DERIVATIVE CHEIL INDUSTRIES INC. (KR) 2001-04-17 US disclosed
US-6174649-B1 THERMOSTABILITY AND PHOTOELECTRIC CHARACTERISTICS SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 2001-01-16 US disclosed
US-5998101-A Cinnamate-containing photopolymer for orientation film of liquid crystal display (LCD) and method of forming the orientation film using the photopolymer SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-12-07 US disclosed