Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915189 | 0.82 | POLB (0.69) | POLBPARP14ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1413142 | 0.81 | MCL1 (0.50) | POLBKDM4EKMT2AMEN1MAPT | |
| SCHEMBL2124660 | 0.79 | KEAP1 (1.00) | KEAP1RECQLPARP14ALDH1A1KDM4E | |
| SCHEMBL6005274 | 0.79 | KEAP1 (0.71) | KEAP1RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL10780391 | 0.79 | KEAP1 (0.71) | KEAP1RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL2128507 | 0.76 | KEAP1 (0.68) | KEAP1RECQLPARP14ALDH1A1KDM4E | |
| SCHEMBL11793189 | 0.76 | KEAP1 (0.67) | KEAP1RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL7441407 | 0.76 | KEAP1 (0.67) | KEAP1RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL18638259 | 0.76 | KEAP1 (0.67) | KEAP1RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL29254256 | 0.76 | KEAP1 (0.67) | KEAP1RECQLALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010890-A2 | PROCESS OF SYNTHESIS OF FLUORESCENT PROTEASE SUBSTRATES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-02-15 | — | — | WO | claimed |
| JP-4232092-A | — | — | None | — | — | JP | disclosed |
| EP-0394563-B1 | Cyan dyes in dye-donor elements for thermal dye transfer | AGFA GEVAERT NV (BE) | 1994-03-09 | — | — | EP | disclosed |
| JP-H04232092-A | THERMOSENSITIVE RECORDING MATERIAL | CIBA GEIGY AG | 1992-08-20 | — | — | JP | disclosed |
| US-5021393-A | Stable quinonediimine dyes | AGFA-GEVAERT, N.V. (BE) | 1991-06-04 | — | — | US | disclosed |
| EP-0394563-A1 | Cyan dyes in dye-donor elements for thermal dye transfer | AGFA-GEVAERT N.V. (BE) | 1990-10-31 | — | — | EP | disclosed |
| US-4921535-A | Heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |