Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078555 | 0.82 | KEAP1 (0.55) | KEAP1RECQLKDM4EPARP14KMT2A | |
| SCHEMBL29901800 | 0.82 | KEAP1 (0.55) | KEAP1RECQLKDM4EPARP14KMT2A | |
| SCHEMBL12768022 | 0.82 | PSIP1 (0.73) | PSIP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2124660 | 0.81 | KEAP1 (1.00) | KEAP1RECQLALDH1A1HPGDKDM4E | |
| SCHEMBL28028822 | 0.81 | GLO1 (0.62) | KEAP1RECQLALDH1A1HPGDKDM4E | |
| SCHEMBL10808948 | 0.81 | KEAP1 (0.57) | KEAP1RECQLALDH1A1HPGDKDM4E | |
| SCHEMBL4649512 | 0.80 | TRPV1 (0.50) | KDM4EKMT2AMEN1MAPT | |
| SCHEMBL10780391 | 0.80 | KEAP1 (0.71) | KEAP1RECQLALDH1A1HPGDKDM4E | |
| SCHEMBL6005274 | 0.80 | KEAP1 (0.71) | KEAP1RECQLALDH1A1HPGDKDM4E | |
| SCHEMBL3860044 | 0.80 | KEAP1 (0.56) | KEAP1RECQLALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583276-A | IRE1 alpha inhibitors and uses thereof | 加利福尼亚大学董事会 | 2023-08-11 | — | — | CN | disclosed |
| CN-104969406-B | Electrolyte solution for electrochemical device and electrochemical device | 富士胶片和光纯药株式会社 | 2018-11-02 | — | — | CN | disclosed |
| EP-2474545-B1 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-2426129-B1 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2016-11-02 | — | — | EP | disclosed |
| EP-2455382-B1 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2016-10-26 | — | — | EP | disclosed |
| CN-104969406-A | Electrolyte solution for electrochemical device and electrochemical device | WAKO PURE CHEM IND LTD | 2015-10-07 | — | — | CN | disclosed |
| US-20120135904-A1 | LUBRICANT COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2444474-A1 | LUBRICANT COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20080286233-A1 | PIPERIZINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286233-A1 | PIPERIZINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, HPN, PREP | KEAP1 196/4885RECQL 3722/4885PSIP1 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.