⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748497 | 0.76 | — | — | |
| SCHEMBL20517132 | 0.73 | — | — | |
| SCHEMBL31748286 | 0.70 | NPSR1 (0.37) | — | |
| SCHEMBL24506333 | 0.70 | POLB (0.34) | — | |
| SCHEMBL21776576 | 0.69 | MCL1 (0.39) | — | |
| SCHEMBL31055636 | 0.69 | HDAC6 (0.37) | — | |
| SCHEMBL27293556 | 0.67 | TOP2A (0.36) | — | |
| SCHEMBL9526242 | 0.67 | COMT (0.49) | — | |
| SCHEMBL31055652 | 0.67 | GAA (0.41) | — | |
| SCHEMBL9526222 | 0.67 | PCSK9 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | claimed |
| EP-3777979-B1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2024-01-17 | — | — | EP | claimed |
| US-11440886-B2 | Anti-inflammatory compound, and preparation and use thereof | E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd. (CN) | 2022-09-13 | — | — | US | claimed |
| EP-1931758-A2 | STAIN REMOVAL | Unilever Plc (GB) | 2008-06-18 | — | — | EP | claimed |
| CN-1317268-C | 2,6-dimethylpyridine preparation method | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-05-23 | — | — | CN | claimed |
| WO-2007042140-A2 | STAIN REMOVAL | UNILEVER PLC (GB) | 2007-04-19 | — | — | WO | claimed |
| CN-1733729-A | 2,6-dimethylpyridine preparation method | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-02-15 | — | — | CN | claimed |
| US-20260048025-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | NATURAL EXTRACTION SYS LLC (US) | 2026-02-19 | — | — | US | disclosed |
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250388541-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
| US-12409152-B2 | Compositions and methods related to dissolved oxides | Natural Extraction Systems, LLC (US) | 2025-09-09 | — | — | US | disclosed |
| EP-3777979-B1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2024-01-17 | — | — | EP | disclosed |
| CN-110407741-B | Anti-inflammatory compound and preparation and application thereof | 启元生物(杭州)有限公司 | 2023-03-21 | — | — | CN | disclosed |
| WO-2006084210-A9 | HIF MODULATING COMPOUNDS AND METHODS OF USE THEREOF | UNIV CALIFORNIA SAN DIEGO (US) | 2006-10-26 | — | — | WO | disclosed |
| WO-2006084210-A2 | HIF MODULATING COMPOUNDS AND METHODS OF USE THEREOF | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2006-08-10 | — | — | WO | disclosed |
| CN-1736986-A | Polyhydroxy stilbenes compound preparation and uses as drugs for suppressing SARS | UNIV DALIAN TECH (CN) | 2006-02-22 | — | — | CN | disclosed |
| CN-1733729-A | 2,6-dimethylpyridine preparation method | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-02-15 | — | — | CN | disclosed |
| CN-1032648-C | Process for preparation of platelet activating factor antagonist | FIZER LTD (GB) | 1996-08-28 | — | — | CN | disclosed |
| CN-1055925-A | Pyridine derivate and preparation method thereof | ICI PLC (GB) | 1991-11-06 | — | — | CN | disclosed |
| CN-1032439-A | A kind of preparation method of platelet-activating factor antagonist | PFIZER LTD (GB) | 1989-04-19 | — | — | CN | disclosed |