Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513428 | 0.74 | ALDH1A1 (0.50) | COMTSMN1; SMN2DDB1CRBNALDH1A1 | |
| SCHEMBL7861231 | 0.73 | SMN1; SMN2 (0.60) | COMTSMN1; SMN2NOTUMDDB1CRBN | |
| SCHEMBL9370346 | 0.72 | POLB (0.64) | SMN1; SMN2NOTUMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL1127502 | 0.72 | ATM (0.48) | COMTSMN1; SMN2NOTUMDDB1CRBN | |
| SCHEMBL14827200 | 0.71 | COMT (0.54) | COMTALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL8142857 | 0.68 | ALDH1A1 (0.53) | COMTNOTUMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14827201 | 0.68 | COMT (0.77) | COMT | |
| SCHEMBL30613481 | 0.68 | COMT (0.49) | COMTSMN1; SMN2NOTUMDDB1CRBN | |
| SCHEMBL791652 | 0.67 | — | — | |
| Formic Acid SCHEMBL27390152 | 0.67 | ATM (0.53) | COMTNOTUMDDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |