Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227871 | 0.81 | PTGS2 (0.40) | ALDH1A1BRD4KDM4EL3MBTL1 | |
| SCHEMBL11436206 | 0.77 | ALDH1A1 (0.56) | PCSK9ALDH1A1HPGDLMNAHTT | |
| SCHEMBL11374766 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL10513428 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL6444709 | 0.72 | PCSK9 (0.73) | PCSK9ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| Biphenyl SCHEMBL27274937 | 0.70 | KDM4E (0.48) | ALDH1A1LMNABRD4KDM4EKMT2A | |
| SCHEMBL12864319 | 0.69 | BRD4 (0.47) | ALDH1A1BRD4KDM4ESMN1; SMN2GLO1 | |
| SCHEMBL9273371 | 0.68 | BRD4 (0.46) | PCSK9ALDH1A1HPGDLMNAHTT | |
| SCHEMBL791652 | 0.67 | — | — | |
| SCHEMBL1964715 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HPGDBRD4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |