SCHEMBL7916528

SCHEMBL7916528

Oc1c(F)c(F)c(C(F)(c2c(F)c(F)c(O)c(F)c2F)C(F)(F)F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683688 0.78 ESR1 (0.33)
SCHEMBL186352 0.77 SMN1; SMN2 (0.40)
SCHEMBL7917304 0.77
SCHEMBL26948675 0.72 SMN1; SMN2 (0.38)
SCHEMBL69958 0.71 ESR1 (0.32)
SCHEMBL1644921 0.71
SCHEMBL8617027 0.70 THRB (0.30)
SCHEMBL8416053 0.70 THRB (0.30)
SCHEMBL8618193 0.70 THRB (0.30)
SCHEMBL8613268 0.70 THRB (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217995-B1 TRANSPARENT POLYCARBONATE OR POLYESTERCARABONATE CONTAINING CYCLIC ALIPHATIC GROUP, HAVING A VISIBLE LIGHT TRANSMITTANCE MORE THAN 80% AND A GLASS TRANSITION TEMPERATURE LESS THAN 80 DEGREE C. EXHIBIT BIREFRINGENCE INDEX LESS THAN 15 NM MITSUBISHI CHEMICAL CORPORATION (JP) 2001-04-17 US disclosed