Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.67 |
| ▸ | PDE4A | P27815 | 19/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950936 | 0.92 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6951109 | 0.89 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6950329 | 0.86 | PDE4D (0.88) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7051464 | 0.84 | PDE4D (0.76) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6949287 | 0.82 | PDE4D (0.55) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6954572 | 0.79 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6948894 | 0.76 | PDE4A (0.74) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6836442 | 0.76 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6954576 | 0.76 | PDE4D (0.70) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6950907 | 0.76 | PDE4D (0.70) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211203-B1 | RESPIRATORY SYSTEM DISORDERS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-04-03 | — | — | US | disclosed |
| WO-1998007715-A9 | NOVEL BENZOFURAN-4-CARBOXAMIDES | BYK GULDEN LOMBERG CHEM FAB (DE) | 1999-04-29 | — | — | WO | disclosed |